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> 대한결핵 및 호흡기학회 > 대한결핵및호흡기학회 추계학술발표초록집 > 127권 0호

PE-006 : The effect of vitamin C in patients with severe viral pneumonia with respiratory failure

PE-006 : The effect of vitamin C in patients with severe viral pneumonia with respiratory failure

( Song-i Lee ) , ( Jin-won Huh ) , ( Jae-seung Lee ) , ( Sang Bum Hong )

- 발행기관 : 대한결핵 및 호흡기학회

- 발행년도 : 2019

- 간행물 : 대한결핵및호흡기학회 추계학술발표초록집, 127권 0호

- 페이지 : pp.424-424 ( 총 1 페이지 )


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논문제목
초록(외국어)
Purpose: Vitamin C is a well-known antioxidant and a few papers reported to improve symptoms and prognosis in sepsis and pneumonia. In this study, we studied the effect of vitamin C when used in viral pneumonia patients with severe respiratory failure. Methods: This is a single center, retrospective review study of patients admitted to the medical intensive care unit from January 2015 to April 2017. There were total 201 patients with viral pneumonia, among them 35 patients used vitamin C. We performed statistical analysis by matching age and baseline characteristics that statistically different of these patients. Results: The baseline characteristics of the patients had a few differences between vit c group and non-vit c group such as age (59.6 ± 14.8 vs. 65.9 ± 14.3, p=0.025), extracorporeal membrane oxygenation (ECMO) (28.6% vs. 5.4%, p<0.001) and procalcitonin ((5.4 ± 10.2 vs. 12.6 ± 27.4, p=0.039). The 28d mortality was no difference between two groups (20.0% vs. 24.7%, p=0.327). In matched group, the 28d mortality was not significant difference between two groups (20.0 % vs. 37.1 %, p=0.073). Besides shock reversal within 14days (45.7% vs. 31.4%, p=0.220) and recovery after acute kidney injury (52.9% vs. 55.6%, p=0.877) were also no different between two groups. Vitamin C was not prognostic factor for the mortality (p=0.334). Conclusion: Adjunctive intravenous vitamin C therapy alone did not reduce 28d mortality in patients with severe viral pneumonia with respiratory failure.

논문정보
  • - 주제 : 의약학분야 > 내과학
  • - 발행기관 : 대한결핵 및 호흡기학회
  • - 간행물 : 대한결핵및호흡기학회 추계학술발표초록집, 127권 0호
  • - 발행년도 : 2019
  • - 페이지 : pp.424-424 ( 총 1 페이지 )
  • - UCI(KEPA) : I410-ECN-0102-2021-500-000608694
저널정보
  • - 주제 : 의약학분야 > 내과학
  • - 성격 : 학술발표
  • - 간기 : 연간
  • - 국내 등재 : -
  • - 해외 등재 : -
  • - ISSN :
  • - 수록범위 : 1960–2020
  • - 수록 논문수 : 7073