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> 대한본초학회 > 대한본초학회지(본초분과학회지) > 25권 2호

해양 유래 한약재의 여드름균에 대한 항균 효능 연구

Antimicrobial activities of ethanolic extracts of marine resources against Propionibacterium acnes

김상찬 ( Sang Chan Kim ) , 박숙자 ( Sook Jahr Park ) , 박찬익 ( Chan Ik Park )

- 발행기관 : 대한본초학회

- 발행년도 : 2010

- 간행물 : 대한본초학회지(본초분과학회지), 25권 2호

- 페이지 : pp.65-70 ( 총 6 페이지 )


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4,500
논문제목
초록(외국어)
Objectives: Biological activities of marine resources have been rarely evaluated compared with other herbal medicines. In the present study, we aimed to evaluate antimicrobial activities of aqueous and ethanolic extracts of five marine resources(Porphyra tenera, Laminariae Thallus, Sargassum, Ostreae Concha, Maliotidis Concha) against Propionibacterium acnes. Methods: Aqueous axtracts of five marine resources were prepared by decocting in tenfold tap water for 3 h. Etanolic extracts were obtained by extracting five marine resources with tenfold ethanol for 72 h at room temperature. The zone of growth inhibition and minimum inhibitory concentration (MIC) were determined against P. acnes after incubation for 48 h under anaerobic condition. Results: Ethanolic extracts of Porphyra tenera exhibited potent antimicrobial effects(MIC 62.5㎍/㎖ against KCTC3320, MIC 31.25㎍/㎖ against KCTC5527). However, all aqueous extracts tested had no effects on the growth inhibition of P. acnes. In addition, four ethanolic extracts except Porphyra tenera showed little inhibitory effect. Conclusions: These results indicate that ethanolic extracts of Porphyra tenera has antimicrobial activities against P. acnes and also warrant further development of Porphyra tenera extracts as a natural anti-acne agent.

논문정보
  • - 주제 : 의약학분야 > 기초한의학
  • - 발행기관 : 대한본초학회
  • - 간행물 : 대한본초학회지(본초분과학회지), 25권 2호
  • - 발행년도 : 2010
  • - 페이지 : pp.65-70 ( 총 6 페이지 )
  • - UCI(KEPA) : I410-ECN-0102-2012-510-001669701
저널정보
  • - 주제 : 의약학분야 > 기초한의학
  • - 성격 : 학술지
  • - 간기 : 격월
  • - 국내 등재 : KCI 등재
  • - 해외 등재 : -
  • - ISSN : 1229-1765
  • - 수록범위 : 1986–2021
  • - 수록 논문수 : 1625