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> 대한예방치과·구강보건학회 > 대한구강보건학회지 > 34권 1호

원저 : 손바닥 선인장 열매 추출물의 Streptococcus mutans에 대한 성장 억제 효과

Original Articles : In vitro growth inhibition of Streptococcus mutans by extract of prickly pear (Opuntia ficus-indica var. saboten Makino)

정은주 ( Eun Ju Jung ) , 홍석진 ( Suk Jin Hong ) , 최정이 ( Jeoung Iee Choi ) , 정성숙 ( Seong Soog Jeong ) , 오한나 ( Han Na Oh ) , 이혜진 ( Hye Jin Lee ) , 최충호 ( Choong Ho Choi )

- 발행기관 : 대한예방치과·구강보건학회

- 발행년도 : 2010

- 간행물 : 대한구강보건학회지, 34권 1호

- 페이지 : pp.28-35 ( 총 8 페이지 )


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4,500
논문제목
초록(외국어)
Objectives. Antimicrobial activity of extract of prickly pear (Opuntia ficus-indica var. saboten Makino; OFI) has been reported. This study examined effects of OFI extract on the growth of Streptococcus mutans. Methods. OFI was extracted by 85% methanol using an ultrasonic extraction method. The agar plate dilution method was used to count the CFU of viability of S. mutans KCTC 3065 that was determined by enumeration (colony forming units) in an agar dilution assay using no OFI (control), or 5, 20, and 50 mg/mL OFI following incubation for 0, 6, 12, and 24 h. The cytotoxicity of OFI extract (0, 5, 10, 20, 40, 50 mg/mL) was evaluated for human gingival fibroblasts by a formazan-based viability. Results. S. mutans growth was reduced by the OFI extract. The number of viable S. mutans was reduced significantly with increasing OFI concentration and incubation time (both p<0.001). The viable counts of S. mutans cultured with 20 and 50 mg/mL OFI decreased gradually but appreciably (>88.7%) by 6 h and no S. mutans remained when cultured with 50 mg/mL at 24 h. OFI concentrations of 40 and 50 mg/mL were cytotoxic to fibroblasts. Conclusions. OFI displays S. mutans inhibitory activity, and may be potential exploited as an oral hygiene agent for the prevention of dental caries.

논문정보
  • - 주제 : 의약학분야 > 기초치의학
  • - 발행기관 : 대한예방치과·구강보건학회
  • - 간행물 : 대한구강보건학회지, 34권 1호
  • - 발행년도 : 2010
  • - 페이지 : pp.28-35 ( 총 8 페이지 )
  • - UCI(KEPA) : I410-ECN-0102-2012-510-001063881
저널정보
  • - 주제 : 의약학분야 > 기초치의학
  • - 성격 : 학술지
  • - 간기 : 계간
  • - 국내 등재 : KCI 등재
  • - 해외 등재 : -
  • - ISSN : 1225-388x
  • - 수록범위 : 1967–2021
  • - 수록 논문수 : 1675