This study examines a regulatory agency’s, the U.S. Food and Drug Administration (FDA), policy management regarding genetically modified (GM) food labeling using an advocacy coalition framework (ACF). Specifically, this study highlights the FDA’s blame-avoiding motivation as a policy management tool. Conclusively, the FDA shows a blame-avoiding attitude which remains a keynote of current policy (i.e., voluntary GM food labeling) since pro-GM food labeling advocacy’s perceived potential benefits by the FDA’s potential policy change or revision requires imposing perceived potential costs on anti-food labeling advocacy. Furthermore, the FDA shirked a consideration of other possible policy alternatives such as (i) implementing a mandatory non-GMO labeling, (ii) requiring GMO labeling, and (iii) creating a Pro-GMO or Anti-GMO Campaign.