Background: The exaggerated postprandial lipemia is an important stimulus for atherogenic disease progression because delayed removal of blood-borne triglyceride (TG)-rich lipoproteins encourages direct deposition of lipoprotein remnants on the arterial wall and increases the likelihood that low-density lipoprotein cholesterol will undergo disease-accelerating oxidative modification. Objective: This study was performed to evaluate the impact of visceral fat on postprandial TG clearance in non-diabetic Korean men. Design: Fifty-one men (mean age: 47 years) referring to the same occupational district, not on hypolipidemic drugs and without any other chronic disease, performed multiple TG profile (at 8 hours-fasting, and every 30min after breakfast for 8 hours) after ingestion of fast food (Big Mac, French fries, and Coca-Cola). The visceral fat (VF) measured by abdominal computed tomography. Results: TG values (mg/dl) were 124.2 (low visceral fat group, VF ＜ 130 cm2) and 179.4 (high visceral fat group, VF > 130 cm2) at fasting (p=0.005), peak TG values were 265.3 vs. 349.6 (p=0.02) and reached at 4-4.5h after breakfast, and area under curve (AUC) were 1514 vs. 2929 8h after meal. Remnant lipoprotein-cholesterol values (mg/dL) were 26.1 vs. 35.6 (p=0.007) at fasting, and 29.3 vs. 39.6 (p=0.006) at 3.5h after meal. Fasting blood glucose (mg/dL), and insulin levels (pmol/L) were 97 vs. 112 (p=0.004), and 36.7 vs. 58.2 (p=0.004). Glucose and insulin AUC 8h after meal were 823 vs. 957.9 (p=0.013) and 118.4 vs. 225.1 (p=0.000). And Log HOMA_insulin resistance were 0.03 vs. 0.27 (p=0.01). Conclusions: We observed persistence of elevated TG level in the blood after ingestion of a high-fat test meal. The increments are directly determined by fasting TG level and the amount of visceral fat. Fasting TG level seems the major nutritional determinant of postprandial TG clearance.