In the present study the whole plant of Ammania baccifera Linn was extracted with petroleum ether, chloroform, ehty1 acetate and ethanol. The extracts were vacuum dried to yield the respective petroleum ether (PEE), chloroform (CE), ethy1 acetate (EAE) and ethanol extracts (EE). PEE, CE, EAE and EE were evaluated for their antipyretic and diuretic activity at 200 mg/kg dose level. Significant antipyretic activity was associated with PEE, CE, EAE and EE CE was found to exhibit higher antipyretic activity as paracetamol at 100 mg/kg dose level. Significant diuretic activity was exhibited by EAE, EE and PEE. The present study supports the claims of Ammania baccifera mentioned in the Indian system of medicine.