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> 한국생약학회 > Natural Product Sciences > 14권 4호

Articles : Antioxidant and Anti-inflammatory Activities of Equisetum hyemale

Articles : Antioxidant and Anti-inflammatory Activities of Equisetum hyemale

( Eun Young Park ) , ( Hoon Jeon )

- 발행기관 : 한국생약학회

- 발행년도 : 2008

- 간행물 : Natural Product Sciences, 14권 4호

- 페이지 : pp.239-243 ( 총 5 페이지 )


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논문제목
초록(외국어)
Equisetum hyemale L. has been prescribed widely as a traditional medicine for the treatment of inflammatory diseases such as rheumatoid arthritis, conjunctivitis, pyelonephritis. In order to identification the mechanism, we examined an antioxidant and anti-inflammatory activity of 85% methanol extract of E. hyemale. In this study E. hyemale exhibited strong scavenging effect on 1,1-diphenyl-2-picrylhydrazyl (DPPH) free radical, superoxide radical, and nitric oxide. To elucidate the anti-inflammatory properties of E. hyemale, we investigated the inhibition effects of nitric oxide and IL-6 by E. hyemale in IFN-gamma and LPS-stimulated mouse peritoneal macrophages. E. hyemale suppressed nitric oxide, IL-6 production and iNOS expression dose-dependently without notable cytotoxic activity. These data suggest that E. hyemale might be useful in inflammatory diseases by inhibiting the free radicals and inflammatory mediators.

논문정보
  • - 주제 : 의약학분야 > 약화학
  • - 발행기관 : 한국생약학회
  • - 간행물 : Natural Product Sciences, 14권 4호
  • - 발행년도 : 2008
  • - 페이지 : pp.239-243 ( 총 5 페이지 )
  • - UCI(KEPA) : I410-ECN-0102-2009-510-020131910
저널정보
  • - 주제 : 의약학분야 > 약화학
  • - 성격 : 학술지
  • - 간기 : 계간
  • - 국내 등재 : KCI 등재
  • - 해외 등재 : - / SCOPUS
  • - ISSN : 1226-3907
  • - 수록범위 : 1995–2020
  • - 수록 논문수 : 1144