Objectives : In this study, we intended to make the foundation of the development of acupuncture tissue model as comparing the needle sensation of six kinds of tissue models and Zusanli (ST36) with the needle force measurement system. Methods : When practitioners did twisting-rotating acupuncture needle manipulation after inserting the needle into six kinds of tissue models, they quantified the similarity sense to the sensation of Zusanli (ST36) with the NRS (Numeric Rating scale). As needle force measurement system did twisting-rotating Acupuncture needle manipulation after inserting needle into Zusanli (ST36) of human and six kinds of tissue models, it can calculate the coefficient of viscosity by measuring the torsion friction. We compare the NRS of practitioners` needle sensation to the coefficient of viscosity of needle force measurement systems. Result : As practitioners` NRS assessment to quantify needle sensation, apple and cucumber showed 70% similarity to Zusanli (ST36). As needle force measurement system`s coefficient of viscosity, apple and cucumber`s coefficient of viscosity were similar to Zusanli (ST36)`s. Conclusions : In this study, We compared the practitioners` needle sensation of Zusanli (ST36) and six kinds of tissue models with needle force measurement system that can quantify the needle sensation. As the result, we concluded that practitioners` needle sensation is similar to measured needle sensation. It seems that the acupuncture practice model implementing the needle sensation to specific acupuncture points can be built based on the system in this study.